Charting the molecular landscape of tumors
What are the characteristics and vulnerabilities of cancer cells? Recurrent copy number aberration of a single gene is a classical sign of its involvement in tumor development. In many cases tumors become ...
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Understanding the regulation of the molecular landscape
How are cellular networks regulated? Understanding the basic molecular regulatory mechanisms that underlie the cancer landscape is important for several reasons. First, it allows more accurate intervention ...
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Mapping the molecular landscape to optimal treatments
What is the best treatment for each patient? In this theme we developed a number of approaches to map molecular profiles of tumors to optimal treatments. These approaches include 1) supervised approaches ...
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